HCSGD entry for CRHR2

1. General information

Official gene symbolCRHR2
Entrez ID1395
Gene full namecorticotropin releasing hormone receptor 2
Other gene symbolsCRF-RB CRF2 CRFR2 HM-CRF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005179Hormone activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0015056Corticotrophin-releasing factor receptor activityIEAmolecular_function
GO:0016525Negative regulation of angiogenesisIEAbiological_process
GO:0043950Positive regulation of cAMP-mediated signalingIEAbiological_process
GO:0043951Negative regulation of cAMP-mediated signalingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58937619390.86422934920.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1064729339
GSE13712_SHEARDown-0.0081589768
GSE13712_STATICDown-0.1277186000
GSE19018Up0.0536177799
GSE19899_A1Up0.0150733192
GSE19899_A2Up0.1669907296
PubMed_21979375_A1Up0.1314121565
PubMed_21979375_A2Up0.0831748617
GSE35957Up0.0212748637
GSE36640Up0.0455648314
GSE54402Up0.0337781529
GSE9593Up0.0519017684
GSE43922Up0.1580306763
GSE24585Up0.0939392682
GSE37065Down-0.1109398765
GSE28863_A1Down-0.0969965161
GSE28863_A2Up0.0820817770
GSE28863_A3Up0.2097077261
GSE28863_A4Up0.1711991982
GSE48662Down-0.0425673124

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017454MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.