HCSGD entry for CRAT
1. General information
| Official gene symbol | CRAT |
|---|---|
| Entrez ID | 1384 |
| Gene full name | carnitine O-acetyltransferase |
| Other gene symbols | CAT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004092 | Carnitine O-acetyltransferase activity | IDA | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005777 | Peroxisome | IDA | cellular_component |
| GO:0005782 | Peroxisomal matrix | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0016746 | Transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0019254 | Carnitine metabolic process, CoA-linked | IDA | biological_process |
| GO:0033540 | Fatty acid beta-oxidation using acyl-CoA oxidase | TAS | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1291345922 | 0.8074412218 | 0.7298586214 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0094753440 |
| GSE13712_SHEAR | Down | -0.0812504972 |
| GSE13712_STATIC | Up | 0.0008215231 |
| GSE19018 | Up | 0.3860168894 |
| GSE19899_A1 | Down | -0.3120014280 |
| GSE19899_A2 | Up | 0.2164239933 |
| PubMed_21979375_A1 | Up | 0.0872843792 |
| PubMed_21979375_A2 | Up | 0.1578158404 |
| GSE35957 | Up | 0.1660316923 |
| GSE36640 | Up | 0.3951056464 |
| GSE54402 | Down | -0.0102764788 |
| GSE9593 | Up | 0.2724227750 |
| GSE43922 | Down | -0.2294900701 |
| GSE24585 | Up | 0.9148585174 |
| GSE37065 | Down | -0.2309916867 |
| GSE28863_A1 | Up | 0.4291897073 |
| GSE28863_A2 | Up | 0.2428839746 |
| GSE28863_A3 | Down | -0.1626710861 |
| GSE28863_A4 | Down | -0.0897660270 |
| GSE48662 | Up | 0.1690157462 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Carnitine | DB00583 | APRD01070 |
| Coenzyme A | DB01992 | EXPT00991 |
| (3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium | DB02648 | EXPT00038 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020803 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
