HCSGD entry for CR2
1. General information
| Official gene symbol | CR2 |
|---|---|
| Entrez ID | 1380 |
| Gene full name | complement component (3d/Epstein Barr virus) receptor 2 |
| Other gene symbols | C3DR CD21 CR CVID7 SLEB9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004875 | Complement receptor activity | NAS | molecular_function |
| GO:0004888 | Transmembrane signaling receptor activity | NAS | molecular_function |
| GO:0005886 | Plasma membrane | NAS | cellular_component |
| GO:0006955 | Immune response | NAS | biological_process |
| GO:0006958 | Complement activation, classical pathway | IEA | biological_process |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0042113 | B cell activation | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0043235 | Receptor complex | IDA | cellular_component |
| GO:0045087 | Innate immune response | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8324546142 | 0.3271401011 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0221927296 |
| GSE13712_SHEAR | Down | -0.0347664557 |
| GSE13712_STATIC | Down | -0.1053262439 |
| GSE19018 | Down | -0.0823446400 |
| GSE19899_A1 | Up | 0.1618913905 |
| GSE19899_A2 | Up | 0.0729224089 |
| PubMed_21979375_A1 | Up | 0.0311941648 |
| PubMed_21979375_A2 | Down | -0.1845976107 |
| GSE35957 | Up | 0.2380653465 |
| GSE36640 | Down | -0.0003512725 |
| GSE54402 | Up | 0.0172855532 |
| GSE9593 | Up | 0.1161335416 |
| GSE43922 | Up | 0.0194052339 |
| GSE24585 | Down | -1.1545594847 |
| GSE37065 | Up | 0.0235913695 |
| GSE28863_A1 | Down | -0.1196104156 |
| GSE28863_A2 | Down | -0.0660673732 |
| GSE28863_A3 | Up | 0.2856111836 |
| GSE28863_A4 | Down | -0.0317609212 |
| GSE48662 | Up | 0.0205316798 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021795 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
