HCSGD entry for AGPAT6
1. General information
| Official gene symbol | AGPAT6 |
|---|---|
| Entrez ID | 137964 |
| Gene full name | 1-acylglycerol-3-phosphate O-acyltransferase 6 |
| Other gene symbols | 1-AGPAT 6 LPAAT-zeta LPAATZ TSARG7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002071 | Glandular epithelial cell maturation | IEA | biological_process |
| GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity | IDA | molecular_function |
| GO:0004366 | Glycerol-3-phosphate O-acyltransferase activity | IDA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA IEA ISS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006631 | Fatty acid metabolic process | IEA | biological_process |
| GO:0006637 | Acyl-CoA metabolic process | IDA | biological_process |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006654 | Phosphatidic acid biosynthetic process | TAS | biological_process |
| GO:0006656 | Phosphatidylcholine biosynthetic process | IDA | biological_process |
| GO:0007595 | Lactation | IEA ISS | biological_process |
| GO:0008610 | Lipid biosynthetic process | ISS | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0016024 | CDP-diacylglycerol biosynthetic process | IEA | biological_process |
| GO:0019432 | Triglyceride biosynthetic process | IDA IEA ISS TAS | biological_process |
| GO:0040014 | Regulation of multicellular organism growth | IEA | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046339 | Diacylglycerol metabolic process | IEA | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1556168725 | 0.9585764941 | 0.7836707863 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2276471554 |
| GSE13712_SHEAR | Up | 0.0847810623 |
| GSE13712_STATIC | Up | 0.0610102584 |
| GSE19018 | Down | -0.0981946379 |
| GSE19899_A1 | Down | -0.0152610190 |
| GSE19899_A2 | Up | 0.1722933341 |
| PubMed_21979375_A1 | Down | -0.0029749960 |
| PubMed_21979375_A2 | Up | 0.1378750077 |
| GSE35957 | Up | 0.0127202685 |
| GSE36640 | Up | 0.1224479452 |
| GSE54402 | Up | 0.1041868981 |
| GSE9593 | Up | 0.1646323349 |
| GSE43922 | Up | 0.5843621748 |
| GSE24585 | Down | -0.0466965043 |
| GSE37065 | Down | -0.1144175026 |
| GSE28863_A1 | Up | 0.3073098801 |
| GSE28863_A2 | Up | 0.2007583324 |
| GSE28863_A3 | Down | -0.1196166039 |
| GSE28863_A4 | Up | 0.1152219977 |
| GSE48662 | Up | 0.3190167447 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023711 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036527 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038091 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045662 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052733 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
