HCSGD entry for CPS1

1. General information

Official gene symbolCPS1
Entrez ID1373
Gene full namecarbamoyl-phosphate synthase 1, mitochondrial
Other gene symbolsCPSASE1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000050Urea cycleIEA NAS TASbiological_process
GO:0004087Carbamoyl-phosphate synthase (ammonia) activityIEA IMPmolecular_function
GO:0004175Endopeptidase activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005543Phospholipid bindingIEAmolecular_function
GO:0005730NucleolusIEAcellular_component
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0005980Glycogen catabolic processIMPbiological_process
GO:0006543Glutamine catabolic processIEAbiological_process
GO:0007494Midgut developmentIEAbiological_process
GO:0009636Response to toxic substanceIEAbiological_process
GO:0010043Response to zinc ionIEAbiological_process
GO:0014075Response to amineIEAbiological_process
GO:0016595Glutamate bindingIEAmolecular_function
GO:0019240Citrulline biosynthetic processNASbiological_process
GO:0019433Triglyceride catabolic processIMPbiological_process
GO:0032094Response to foodIEAbiological_process
GO:0032403Protein complex bindingIEAmolecular_function
GO:0032496Response to lipopolysaccharideIDA IEAbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042594Response to starvationIEAbiological_process
GO:0042645Mitochondrial nucleoidIDAcellular_component
GO:0043200Response to amino acidIEAbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0044344Cellular response to fibroblast growth factor stimulusIEAbiological_process
GO:0045909Positive regulation of vasodilationIMPbiological_process
GO:0046209Nitric oxide metabolic processIMPbiological_process
GO:0050667Homocysteine metabolic processIDAbiological_process
GO:0055081Anion homeostasisIEAbiological_process
GO:0060416Response to growth hormoneIEAbiological_process
GO:0070365Hepatocyte differentiationIEAbiological_process
GO:0070409Carbamoyl phosphate biosynthetic processIMPbiological_process
GO:0071320Cellular response to cAMPIEAbiological_process
GO:0071377Cellular response to glucagon stimulusIEAbiological_process
GO:0071400Cellular response to oleic acidIEAbiological_process
GO:0071548Response to dexamethasoneIEAbiological_process
GO:0072341Modified amino acid bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97446317770.00055502830.99999024730.0441356495

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5508098696
GSE13712_SHEARUp0.1481010625
GSE13712_STATICDown-0.0542044902
GSE19018Up0.0998537529
GSE19899_A1Down-0.3092956224
GSE19899_A2Down-2.7370636183
PubMed_21979375_A1Down-2.9146120689
PubMed_21979375_A2Down-1.0619147257
GSE35957Down-0.4046754573
GSE36640Down-3.8092516405
GSE54402Down-1.1322831003
GSE9593Down-0.4785445869
GSE43922Down-1.5540958269
GSE24585Down-0.8159140428
GSE37065Down-0.2188502696
GSE28863_A1Up0.9105516628
GSE28863_A2Up0.1129678236
GSE28863_A3Down-0.3461729655
GSE28863_A4Down-0.1943707254
GSE48662Up0.0815126537

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-17-5pMIMAT0000070MIRT051022CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.