HCSGD entry for MTPN

1. General information

Official gene symbolMTPN
Entrez ID136319
Gene full namemyotrophin
Other gene symbolsGCDP V-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusISScellular_component
GO:0005829CytosolISScellular_component
GO:0006417Regulation of translationNASbiological_process
GO:0006584Catecholamine metabolic processIEAbiological_process
GO:0008290F-actin capping protein complexIDAcellular_component
GO:0010557Positive regulation of macromolecule biosynthetic processISSbiological_process
GO:0010613Positive regulation of cardiac muscle hypertrophyIMPbiological_process
GO:0016049Cell growthIDAbiological_process
GO:0016202Regulation of striated muscle tissue developmentNASbiological_process
GO:0021707Cerebellar granule cell differentiationIEAbiological_process
GO:0030182Neuron differentiationNASbiological_process
GO:0030307Positive regulation of cell growthISSbiological_process
GO:0030424AxonIEAcellular_component
GO:0043403Skeletal muscle tissue regenerationIEAbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0051092Positive regulation of NF-kappaB transcription factor activityISSbiological_process
GO:0051146Striated muscle cell differentiationIEAbiological_process
GO:0051247Positive regulation of protein metabolic processISSbiological_process
GO:2000812Regulation of barbed-end actin filament cappingIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23786581060.00159229130.92384034230.0769003670

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1841663779
GSE13712_SHEARDown-0.5169907455
GSE13712_STATICUp0.2092236232
GSE19018Up0.2044215567
GSE19899_A1Up0.8503035082
GSE19899_A2Down-0.4650480748
PubMed_21979375_A1Down-0.4122044856
PubMed_21979375_A2Down-1.2818656600
GSE35957Up1.3926388668
GSE36640Up0.1156075889
GSE54402Up0.0904713037
GSE9593Up0.4536903634
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-1.7804355075
GSE28863_A2Down-1.9071307850
GSE28863_A3Down-1.3090659087
GSE28863_A4Down-0.9958080247
GSE48662Down-0.3777793393

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT000054Reporter assay;OtherFunctional MTI15538371
hsa-miR-124-3pMIMAT0000422MIRT001834Reporter assayFunctional MTI15806104
hsa-let-7b-5pMIMAT0000063MIRT001850Reporter assayFunctional MTI15806104
hsa-miR-122-5pMIMAT0000421MIRT023322MicroarrayFunctional MTI (Weak)17612493
hsa-miR-21-5pMIMAT0000076MIRT030848MicroarrayFunctional MTI (Weak)18591254
hsa-miR-130b-5pMIMAT0004680MIRT038329CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-3pMIMAT0004493MIRT038976CLASHFunctional MTI (Weak)23622248
hsa-miR-503-5pMIMAT0002874MIRT041109CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043449CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.