HCSGD entry for SRSF12
1. General information
| Official gene symbol | SRSF12 |
|---|---|
| Entrez ID | 135295 |
| Gene full name | serine/arginine-rich splicing factor 12 |
| Other gene symbols | RP11-63L7.3 SFRS13B SFRS19 SRrp35 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000244 | Spliceosomal tri-snRNP complex assembly | NAS | biological_process |
| GO:0000381 | Regulation of alternative mRNA splicing, via spliceosome | IDA | biological_process |
| GO:0000395 | MRNA 5'-splice site recognition | IDA | biological_process |
| GO:0003723 | RNA binding | NAS | molecular_function |
| GO:0005654 | Nucleoplasm | ISS | cellular_component |
| GO:0016482 | Cytoplasmic transport | ISS | biological_process |
| GO:0048025 | Negative regulation of mRNA splicing, via spliceosome | ISS | biological_process |
| GO:0050733 | RS domain binding | NAS | molecular_function |
| GO:0051082 | Unfolded protein binding | NAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7763262604 | 0.5148014969 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0626102876 |
| GSE13712_SHEAR | Down | -0.0318377447 |
| GSE13712_STATIC | Down | -0.0508454831 |
| GSE19018 | Down | -0.3695909024 |
| GSE19899_A1 | Up | 0.1395488771 |
| GSE19899_A2 | Up | 0.0266109550 |
| PubMed_21979375_A1 | Down | -0.2258908731 |
| PubMed_21979375_A2 | Down | -0.1538921662 |
| GSE35957 | Up | 0.1424673792 |
| GSE36640 | Up | 0.2113699940 |
| GSE54402 | Down | -0.0239235037 |
| GSE9593 | Up | 0.2364664671 |
| GSE43922 | Up | 0.0113561598 |
| GSE24585 | Up | 0.0725988530 |
| GSE37065 | Down | -0.0311614893 |
| GSE28863_A1 | Down | -0.1184201504 |
| GSE28863_A2 | Up | 0.0457305891 |
| GSE28863_A3 | Up | 0.2033616055 |
| GSE28863_A4 | Down | -0.2824910989 |
| GSE48662 | Up | 0.0881727279 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019116 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
