HCSGD entry for AFAP1L1
1. General information
| Official gene symbol | AFAP1L1 |
|---|---|
| Entrez ID | 134265 |
| Gene full name | actin filament associated protein 1-like 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002102 | Podosome | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0071437 | Invadopodium | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4910324418 | 0.1740678850 | 0.9999902473 | 0.8075928811 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3220386911 |
| GSE13712_SHEAR | Down | -0.9464661619 |
| GSE13712_STATIC | Down | -0.8279186368 |
| GSE19018 | Up | 0.1143724341 |
| GSE19899_A1 | Up | 0.1105055089 |
| GSE19899_A2 | Up | 0.2755333293 |
| PubMed_21979375_A1 | Up | 0.2104192423 |
| PubMed_21979375_A2 | Down | -0.2271030573 |
| GSE35957 | Down | -0.3073646605 |
| GSE36640 | Down | -1.0501945587 |
| GSE54402 | Up | 0.1988329751 |
| GSE9593 | Up | 0.2557112320 |
| GSE43922 | Up | 0.0450723858 |
| GSE24585 | Up | 0.4677763959 |
| GSE37065 | Up | 0.1236443624 |
| GSE28863_A1 | Down | -0.1241398320 |
| GSE28863_A2 | Up | 0.3001006455 |
| GSE28863_A3 | Up | 0.1358887204 |
| GSE28863_A4 | Up | 0.0816304253 |
| GSE48662 | Down | -0.5083202101 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022265 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026274 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
