HCSGD entry for ADORA1

1. General information

Official gene symbolADORA1
Entrez ID134
Gene full nameadenosine A1 receptor
Other gene symbolsRDC7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000186Activation of MAPKK activityIEAbiological_process
GO:0001609G-protein coupled adenosine receptor activityIEAmolecular_function
GO:0001659Temperature homeostasisIEAbiological_process
GO:0001664G-protein coupled receptor bindingIEAmolecular_function
GO:0001666Response to hypoxiaIEAbiological_process
GO:0001883Purine nucleoside bindingIEAmolecular_function
GO:0002087Regulation of respiratory gaseous exchange by neurological system processIEAbiological_process
GO:0002674Negative regulation of acute inflammatory responseIEAbiological_process
GO:0002686Negative regulation of leukocyte migrationIEAbiological_process
GO:0002793Positive regulation of peptide secretionIEAbiological_process
GO:0003093Regulation of glomerular filtrationIEAbiological_process
GO:0004629Phospholipase C activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006612Protein targeting to membraneIEAbiological_process
GO:0006909PhagocytosisTASbiological_process
GO:0006954Inflammatory responseTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0012505Endomembrane systemIEAcellular_component
GO:0014050Negative regulation of glutamate secretionIEAbiological_process
GO:0014069Postsynaptic densityIEAcellular_component
GO:0016042Lipid catabolic processIEAbiological_process
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0030673AxolemmaIEAcellular_component
GO:0031683G-protein beta/gamma-subunit complex bindingIEAmolecular_function
GO:0032229Negative regulation of synaptic transmission, GABAergicIEAbiological_process
GO:0032244Positive regulation of nucleoside transportIEAbiological_process
GO:0032279Asymmetric synapseIEAcellular_component
GO:0032795Heterotrimeric G-protein bindingIEAmolecular_function
GO:0032900Negative regulation of neurotrophin productionIEAbiological_process
GO:0035307Positive regulation of protein dephosphorylationIEAbiological_process
GO:0035814Negative regulation of renal sodium excretionIEAbiological_process
GO:0042323Negative regulation of circadian sleep/wake cycle, non-REM sleepIEAbiological_process
GO:0042734Presynaptic membraneIEAcellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043195Terminal boutonIEAcellular_component
GO:0043268Positive regulation of potassium ion transportIEAbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0045741Positive regulation of epidermal growth factor-activated receptor activityIEAbiological_process
GO:0045776Negative regulation of blood pressureIEAbiological_process
GO:0045777Positive regulation of blood pressureIEAbiological_process
GO:0045822Negative regulation of heart contractionIEAbiological_process
GO:0045908Negative regulation of vasodilationIEAbiological_process
GO:0046888Negative regulation of hormone secretionIEAbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048167Regulation of synaptic plasticityIEAbiological_process
GO:0048786Presynaptic active zoneIEAcellular_component
GO:0050890CognitionIEAbiological_process
GO:0050965Detection of temperature stimulus involved in sensory perception of painIEAbiological_process
GO:0050995Negative regulation of lipid catabolic processIEAbiological_process
GO:0051967Negative regulation of synaptic transmission, glutamatergicIEAbiological_process
GO:0055118Negative regulation of cardiac muscle contractionIEAbiological_process
GO:0060079Regulation of excitatory postsynaptic membrane potentialIEAbiological_process
GO:0060087Relaxation of vascular smooth muscleIEAbiological_process
GO:0070256Negative regulation of mucus secretionIEAbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45148089360.82853317500.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0415651629
GSE13712_SHEARDown-0.1105967790
GSE13712_STATICDown-0.0583362251
GSE19018Up0.1222738813
GSE19899_A1Up0.1902497960
GSE19899_A2Up0.1783780217
PubMed_21979375_A1Down-0.0636449560
PubMed_21979375_A2Down-0.0437359261
GSE35957Up0.0796564026
GSE36640Up0.0565127476
GSE54402Down-0.0485751679
GSE9593Up0.0709257746
GSE43922Up0.1230551294
GSE24585Up0.0034036289
GSE37065Up0.1030208798
GSE28863_A1Up0.0040854061
GSE28863_A2Up0.0503226500
GSE28863_A3Up0.1046476053
GSE28863_A4Up0.1453194779
GSE48662Down-0.0237059336

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

TheophyllineDB00277 APRD00082 | DB09359
PentoxifyllineDB00806 APRD00121
EnprofyllineDB00824 APRD00273
GabapentinDB00996 APRD00015
AminophyllineDB01223 APRD00329
OxtriphyllineDB01303 -
TheobromineDB01412 -
DefibrotideDB04932 -
TecadenosonDB04954 -
KW-3902DB05360 -
NaxifyllineDB06471 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.