HCSGD entry for NADK2
1. General information
| Official gene symbol | NADK2 |
|---|---|
| Entrez ID | 133686 |
| Gene full name | NAD kinase 2, mitochondrial |
| Other gene symbols | C5orf33 MNADK NADKD1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003951 | NAD+ kinase activity | IDA IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0006741 | NADP biosynthetic process | IEA | biological_process |
| GO:0019674 | NAD metabolic process | IDA IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9085127959 | 0.0406898218 | 0.9999902473 | 0.3802230387 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3431101197 |
| GSE13712_SHEAR | Up | 0.1548940204 |
| GSE13712_STATIC | Up | 0.0402138867 |
| GSE19018 | Down | -0.1457192801 |
| GSE19899_A1 | Down | -0.3935830317 |
| GSE19899_A2 | Down | -0.1913106357 |
| PubMed_21979375_A1 | Down | -0.2306032122 |
| PubMed_21979375_A2 | Down | -0.5166244571 |
| GSE35957 | Up | 0.4094287675 |
| GSE36640 | Down | -0.0558816201 |
| GSE54402 | Down | -0.4631000990 |
| GSE9593 | Down | -0.1360600457 |
| GSE43922 | Down | -0.0587461197 |
| GSE24585 | Down | -0.2751427756 |
| GSE37065 | Down | -0.2966401029 |
| GSE28863_A1 | Up | 0.0159088909 |
| GSE28863_A2 | Up | 0.2308966144 |
| GSE28863_A3 | Down | -0.5070385466 |
| GSE28863_A4 | Down | -0.3224423731 |
| GSE48662 | Up | 0.6812501543 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT041747 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
