HCSGD entry for ENPP6


1. General information

Official gene symbolENPP6
Entrez ID133121
Gene full nameectonucleotide pyrophosphatase/phosphodiesterase 6
Other gene symbolsNPP6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionIDAcellular_component
GO:0005886Plasma membraneIDA IEAcellular_component
GO:0006629Lipid metabolic processIDAbiological_process
GO:0008081Phosphoric diester hydrolase activityIDAmolecular_function
GO:0008889Glycerophosphodiester phosphodiesterase activityIEAmolecular_function
GO:0016042Lipid catabolic processIEAbiological_process
GO:0019695Choline metabolic processIDA IEAbiological_process
GO:0031225Anchored component of membraneIEAcellular_component
GO:0047390Glycerophosphocholine cholinephosphodiesterase activityIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71287989440.80591122680.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0521075486
GSE13712_SHEARDown-0.1117924903
GSE13712_STATICDown-0.1922522571
GSE19018Down-0.1784424357
GSE19899_A1Up0.1010676798
GSE19899_A2Down-0.0610659448
PubMed_21979375_A1Up0.1921787748
PubMed_21979375_A2Up0.0450681765
GSE35957Up0.0364996118
GSE36640Down-0.1435890576
GSE54402Up0.1175935734
GSE9593Up0.0655142803
GSE43922Up0.0069805863
GSE24585Up0.2537290720
GSE37065Down-0.0362574516
GSE28863_A1Down-0.0339940704
GSE28863_A2Up0.0265132185
GSE28863_A3Up0.2034216763
GSE28863_A4Up0.1010756696
GSE48662Up0.1111979415

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019285MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.