HCSGD entry for UROC1
1. General information
| Official gene symbol | UROC1 |
|---|---|
| Entrez ID | 131669 |
| Gene full name | urocanate hydratase 1 |
| Other gene symbols | HMFN0320 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0006548 | Histidine catabolic process | IMP TAS | biological_process |
| GO:0016153 | Urocanate hydratase activity | EXP IDA | molecular_function |
| GO:0019556 | Histidine catabolic process to glutamate and formamide | IEA | biological_process |
| GO:0019557 | Histidine catabolic process to glutamate and formate | IEA | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6167636526 | 0.8767706356 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0600293254 |
| GSE13712_SHEAR | Up | 0.0050241610 |
| GSE13712_STATIC | Up | 0.0151602956 |
| GSE19018 | Up | 0.0015117457 |
| GSE19899_A1 | Down | -0.0686550496 |
| GSE19899_A2 | Down | -0.0060621828 |
| PubMed_21979375_A1 | Up | 0.2184647252 |
| PubMed_21979375_A2 | Up | 0.1566332145 |
| GSE35957 | Down | -0.0971929306 |
| GSE36640 | Up | 0.0983164595 |
| GSE54402 | Up | 0.1688748692 |
| GSE9593 | Down | -0.0441483433 |
| GSE43922 | Up | 0.0532355073 |
| GSE24585 | Down | -0.1347775848 |
| GSE37065 | Down | -0.0446896976 |
| GSE28863_A1 | Down | -0.0327702896 |
| GSE28863_A2 | Up | 0.1889861164 |
| GSE28863_A3 | Up | 0.1340163858 |
| GSE28863_A4 | Up | 0.1662851177 |
| GSE48662 | Up | 0.0807264370 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7e-5p | MIMAT0000066 | MIRT051488 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
