HCSGD entry for DIS3L2

1. General information

Official gene symbolDIS3L2
Entrez ID129563
Gene full nameDIS3 mitotic control homolog (S. cerevisiae)-like 2
Other gene symbolsFAM6A PRLMNS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00001753'-5'-exoribonuclease activityIDA IEAmolecular_function
GO:0000291Nuclear-transcribed mRNA catabolic process, exonucleolyticIMPbiological_process
GO:0000932Cytoplasmic mRNA processing bodyIDAcellular_component
GO:0003723RNA bindingIEAmolecular_function
GO:0004540Ribonuclease activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005844PolysomeTAScellular_component
GO:0007067MitosisIMPbiological_process
GO:0008285Negative regulation of cell proliferationIMPbiological_process
GO:0010587MiRNA catabolic processIEA ISSbiological_process
GO:0019827Stem cell maintenanceIEA ISSbiological_process
GO:0034427Nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'IEAbiological_process
GO:0051306Mitotic sister chromatid separationIMPbiological_process
GO:0090305Nucleic acid phosphodiester bond hydrolysisIDAbiological_process
GO:0090501RNA phosphodiester bond hydrolysisIDAbiological_process
GO:0090503RNA phosphodiester bond hydrolysis, exonucleolyticIDAbiological_process
GO:1990074Polyuridylation-dependent mRNA catabolic processISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62510144750.81731711560.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0086699966
GSE13712_SHEARDown-0.0487014510
GSE13712_STATICDown-0.0088835887
GSE19018Down-0.0895585740
GSE19899_A1Down-0.0061190215
GSE19899_A2Up0.0876332340
PubMed_21979375_A1Up0.6177820507
PubMed_21979375_A2Up0.1554666841
GSE35957Down-0.2196261837
GSE36640Down-0.0690677632
GSE54402Up0.0007667037
GSE9593Down-0.1383006647
GSE43922Down-0.0649742558
GSE24585Up0.0275626291
GSE37065Down-0.0001775193
GSE28863_A1Up0.0966038592
GSE28863_A2Up0.1429124716
GSE28863_A3Up0.1761014404
GSE28863_A4Up0.0464918640
GSE48662Up0.0716259117

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.