HCSGD entry for COL7A1
1. General information
| Official gene symbol | COL7A1 |
|---|---|
| Entrez ID | 1294 |
| Gene full name | collagen, type VII, alpha 1 |
| Other gene symbols | EBD1 EBDCT EBR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005590 | Collagen type VII | TAS | cellular_component |
| GO:0005604 | Basement membrane | IEA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0008544 | Epidermis development | TAS | biological_process |
| GO:0022617 | Extracellular matrix disassembly | TAS | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030574 | Collagen catabolic process | TAS | biological_process |
| GO:0031012 | Extracellular matrix | ISS | cellular_component |
| GO:0042802 | Identical protein binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0272229513 | 0.5977610957 | 0.3833214209 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3887078618 |
| GSE13712_SHEAR | Up | 0.2676456897 |
| GSE13712_STATIC | Up | 0.0378675555 |
| GSE19018 | Down | -0.0940478229 |
| GSE19899_A1 | Up | 0.4173591085 |
| GSE19899_A2 | Down | -0.4570196907 |
| PubMed_21979375_A1 | Up | 1.8721675568 |
| PubMed_21979375_A2 | Up | 0.9295000444 |
| GSE35957 | Down | -0.8356758459 |
| GSE36640 | Down | -0.6581378308 |
| GSE54402 | Up | 0.6726100554 |
| GSE9593 | Up | 0.1418027275 |
| GSE43922 | Up | 0.2324232351 |
| GSE24585 | Down | -0.0349590740 |
| GSE37065 | Up | 0.3570134815 |
| GSE28863_A1 | Down | -0.1664197114 |
| GSE28863_A2 | Up | 0.2378510120 |
| GSE28863_A3 | Up | 0.3057606497 |
| GSE28863_A4 | Up | 0.1268876323 |
| GSE48662 | Down | -0.2626565058 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29c-3p | MIMAT0000681 | MIRT006382 | Luciferase reporter assay | Functional MTI | 21436257 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
