HCSGD entry for BHLHE23
1. General information
| Official gene symbol | BHLHE23 |
|---|---|
| Entrez ID | 128408 |
| Gene full name | basic helix-loop-helix family, member e23 |
| Other gene symbols | BETA4 BHLHB4 bA305P22.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0046548 | Retinal rod cell development | IEA | biological_process |
| GO:0046671 | Negative regulation of retinal cell programmed cell death | IEA | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
| GO:0048050 | Post-embryonic eye morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2857323278 | 0.8216533832 | 0.9851664396 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1178177213 |
| GSE13712_SHEAR | Down | -0.0080576363 |
| GSE13712_STATIC | Down | -0.1236223927 |
| GSE19018 | Down | -0.0917924557 |
| GSE19899_A1 | Up | 0.0447449594 |
| GSE19899_A2 | Down | -0.1611311320 |
| PubMed_21979375_A1 | Down | -0.0376281619 |
| PubMed_21979375_A2 | Down | -0.2492164814 |
| GSE35957 | Up | 0.1483283835 |
| GSE36640 | Up | 0.2577040636 |
| GSE54402 | Up | 0.0359850482 |
| GSE9593 | Down | -0.0038969292 |
| GSE43922 | Up | 0.2326649749 |
| GSE24585 | Up | 0.2901136430 |
| GSE37065 | Up | 0.0098155710 |
| GSE28863_A1 | Down | -0.0278484148 |
| GSE28863_A2 | Down | -0.0139527018 |
| GSE28863_A3 | Up | 0.5458405040 |
| GSE28863_A4 | Up | 0.1332411790 |
| GSE48662 | Up | 0.3365060997 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26021512 | Thymosin Beta-4 Recombinant Adeno-associated Virus Enhances Human Nucleus Pulposus Cell Proliferation and Reduces Cell Apoptosis and Senescence |
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