HCSGD entry for ARHGEF19

1. General information

Official gene symbolARHGEF19
Entrez ID128272
Gene full nameRho guanine nucleotide exchange factor (GEF) 19
Other gene symbolsWGEF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0032321Positive regulation of Rho GTPase activityIEAbiological_process
GO:0032956Regulation of actin cytoskeleton organizationIGIbiological_process
GO:0042060Wound healingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98480416780.02309640210.99999024730.2923539423

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1295756067
GSE13712_SHEARDown-0.7483868903
GSE13712_STATICDown-0.6910429275
GSE19018Down-0.0980761596
GSE19899_A1Down-0.3077748489
GSE19899_A2Down-0.3876336021
PubMed_21979375_A1Down-0.8865892924
PubMed_21979375_A2Down-0.6523200221
GSE35957Down-1.0042976804
GSE36640Down-0.2839720144
GSE54402Down-0.0878980958
GSE9593Down-0.3760150725
GSE43922Up0.1139346677
GSE24585Up0.1606070362
GSE37065Up0.0299671030
GSE28863_A1Up0.0220132631
GSE28863_A2Up0.0481722434
GSE28863_A3Down-0.0837193668
GSE28863_A4Down-0.0438849926
GSE48662Down-0.0738324333

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.