HCSGD entry for ADH5

1. General information

Official gene symbolADH5
Entrez ID128
Gene full namealcohol dehydrogenase 5 (class III), chi polypeptide
Other gene symbolsADH-3 ADHX FALDH FDH GSH-FDH GSNOR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processIEAbiological_process
GO:0003016Respiratory system processIEAbiological_process
GO:0004022Alcohol dehydrogenase (NAD) activityIEAmolecular_function
GO:0005504Fatty acid bindingIDAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0006068Ethanol catabolic processIEAbiological_process
GO:0006069Ethanol oxidationIEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0008270Zinc ion bindingIDA IEAmolecular_function
GO:0009055Electron carrier activityTASmolecular_function
GO:0016491Oxidoreductase activityIEAmolecular_function
GO:0018119Peptidyl-cysteine S-nitrosylationIEAbiological_process
GO:0018467Formaldehyde dehydrogenase activityIDAmolecular_function
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0045777Positive regulation of blood pressureIEAbiological_process
GO:0046294Formaldehyde catabolic processIEAbiological_process
GO:0051409Response to nitrosative stressIEAbiological_process
GO:0051775Response to redox stateIDAbiological_process
GO:0051903S-(hydroxymethyl)glutathione dehydrogenase activityIEA TASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90761338470.03544613430.99999024730.3568256498

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1113922863
GSE13712_SHEARDown-0.3446541286
GSE13712_STATICDown-0.0751511585
GSE19018Down-0.4384920067
GSE19899_A1Down-0.7307619758
GSE19899_A2Down-0.4496079666
PubMed_21979375_A1Down-0.3091464522
PubMed_21979375_A2Down-0.3554125490
GSE35957Up0.6175253327
GSE36640Down-0.0651680715
GSE54402Down-0.3891047289
GSE9593Up0.4005890292
GSE43922Down-0.4332924243
GSE24585Up0.1722586465
GSE37065Down-0.0302428491
GSE28863_A1Up0.2903432163
GSE28863_A2Up0.2926083979
GSE28863_A3Down-0.4729186908
GSE28863_A4Down-0.1664738486
GSE48662Down-0.3468439969

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527
12-Hydroxydodecanoic AcidDB03704 EXPT00021
S-Hydroxymethyl GlutathioneDB04153 EXPT00464

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020534ProteomicsFunctional MTI (Weak)18668040
hsa-miR-106b-5pMIMAT0000680MIRT044260CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.