HCSGD entry for ARL8A
1. General information
| Official gene symbol | ARL8A |
|---|---|
| Entrez ID | 127829 |
| Gene full name | ADP-ribosylation factor-like 8A |
| Other gene symbols | ARL10B GIE2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | NAS | molecular_function |
| GO:0005525 | GTP binding | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0006184 | GTP catabolic process | NAS | biological_process |
| GO:0007059 | Chromosome segregation | ISS | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0031902 | Late endosome membrane | IEA | cellular_component |
| GO:0043014 | Alpha-tubulin binding | ISS | molecular_function |
| GO:0048487 | Beta-tubulin binding | ISS | molecular_function |
| GO:0051233 | Spindle midzone | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0338869344 | 0.8185306181 | 0.4239249049 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2690243134 |
| GSE13712_SHEAR | Up | 0.0097068969 |
| GSE13712_STATIC | Up | 0.1675113723 |
| GSE19018 | Down | -0.3415993538 |
| GSE19899_A1 | Up | 0.2415378486 |
| GSE19899_A2 | Up | 0.9022691533 |
| PubMed_21979375_A1 | Up | 0.5308777716 |
| PubMed_21979375_A2 | Up | 0.7211465639 |
| GSE35957 | Up | 0.3132560575 |
| GSE36640 | Up | 0.7440694605 |
| GSE54402 | Up | 0.2744593812 |
| GSE9593 | Up | 0.5835322045 |
| GSE43922 | Up | 0.3458190018 |
| GSE24585 | Down | -0.0407413359 |
| GSE37065 | Down | -0.1140043828 |
| GSE28863_A1 | Down | -0.4977869042 |
| GSE28863_A2 | Up | 0.1281972264 |
| GSE28863_A3 | Down | -0.5574558767 |
| GSE28863_A4 | Down | -0.1993833311 |
| GSE48662 | Up | 0.4565284482 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | MIRT019232 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027168 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
