HCSGD entry for CNTF

1. General information

Official gene symbolCNTF
Entrez ID1270
Gene full nameciliary neurotrophic factor
Other gene symbolsHCNTF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005127Ciliary neurotrophic factor receptor bindingTASmolecular_function
GO:0005138Interleukin-6 receptor bindingIPImolecular_function
GO:0005615Extracellular spaceICcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0007165Signal transductionNASbiological_process
GO:0008083Growth factor activityIDAmolecular_function
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0040007GrowthIEAbiological_process
GO:0042517Positive regulation of tyrosine phosphorylation of Stat3 proteinIDAbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0043524Negative regulation of neuron apoptotic processIDAbiological_process
GO:0046533Negative regulation of photoreceptor cell differentiationIEAbiological_process
GO:0046668Regulation of retinal cell programmed cell deathIEAbiological_process
GO:0048644Muscle organ morphogenesisIEAbiological_process
GO:0048666Neuron developmentIEAbiological_process
GO:0070120Ciliary neurotrophic factor-mediated signaling pathwayIDAbiological_process
GO:0097058CRLF-CLCF1 complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54742241940.91265322750.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0165499843
GSE13712_SHEARUp0.0386762214
GSE13712_STATICUp0.0994773817
GSE19018Down-0.1086394789
GSE19899_A1Up0.0098839692
GSE19899_A2Up0.1996182524
PubMed_21979375_A1Up0.2421333485
PubMed_21979375_A2Up0.1350962044
GSE35957Up0.2267390133
GSE36640Down-0.4791779461
GSE54402Up0.2304087287
GSE9593Up0.1078823858
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0359966178

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.