HCSGD entry for CNR2

1. General information

Official gene symbolCNR2
Entrez ID1269
Gene full namecannabinoid receptor 2 (macrophage)
Other gene symbolsCB-2 CB2 CX5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001975Response to amphetamineIEAbiological_process
GO:0004949Cannabinoid receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0006955Immune responseTASbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007610BehaviorTASbiological_process
GO:0019233Sensory perception of painIEAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0031234Extrinsic component of cytoplasmic side of plasma membraneIEAcellular_component
GO:0032229Negative regulation of synaptic transmission, GABAergicIEAbiological_process
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0033004Negative regulation of mast cell activationIEAbiological_process
GO:0043204PerikaryonIEAcellular_component
GO:0045759Negative regulation of action potentialIEAbiological_process
GO:0050728Negative regulation of inflammatory responseIEAbiological_process
GO:0051001Negative regulation of nitric-oxide synthase activityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.36110307360.87119963910.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1658292581
GSE13712_SHEARDown-0.0005223964
GSE13712_STATICDown-0.1355706075
GSE19018Down-0.0332261294
GSE19899_A1Up0.0015876121
GSE19899_A2Up0.1293063661
PubMed_21979375_A1Up0.2034476330
PubMed_21979375_A2Up0.0743026104
GSE35957Up0.3037323694
GSE36640Down-0.1031947520
GSE54402Up0.1648007982
GSE9593Down-0.0132181586
GSE43922Up0.0272124125
GSE24585Down-0.0533519376
GSE37065Up0.1183421646
GSE28863_A1Down-0.0122750022
GSE28863_A2Down-0.1041578999
GSE28863_A3Up0.3794147646
GSE28863_A4Up0.2214710165
GSE48662Up0.2639113533

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NabiloneDB00486 APRD01127

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.