HCSGD entry for CNR1

1. General information

Official gene symbolCNR1
Entrez ID1268
Gene full namecannabinoid receptor 1 (brain)
Other gene symbolsCANN6 CB-R CB1 CB1A CB1K5 CB1R CNR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002866Positive regulation of acute inflammatory response to antigenic stimulusIEAbiological_process
GO:0004949Cannabinoid receptor activityIDA IEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayIDAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0007584Response to nutrientIEAbiological_process
GO:0007610BehaviorTASbiological_process
GO:0007613MemoryIEAbiological_process
GO:0008144Drug bindingIEAmolecular_function
GO:0010976Positive regulation of neuron projection developmentIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019233Sensory perception of painIEAbiological_process
GO:0031622Positive regulation of fever generationIEAbiological_process
GO:0031999Negative regulation of fatty acid beta-oxidationIEAbiological_process
GO:0032228Regulation of synaptic transmission, GABAergicIEAbiological_process
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0033004Negative regulation of mast cell activationIEAbiological_process
GO:0033602Negative regulation of dopamine secretionIEAbiological_process
GO:0035094Response to nicotineIEAbiological_process
GO:0042220Response to cocaineIEAbiological_process
GO:0043065Positive regulation of apoptotic processIEAbiological_process
GO:0043278Response to morphineIEAbiological_process
GO:0045471Response to ethanolIEAbiological_process
GO:0045759Negative regulation of action potentialIEAbiological_process
GO:0045776Negative regulation of blood pressureIEAbiological_process
GO:0045777Positive regulation of blood pressureIEAbiological_process
GO:0050796Regulation of insulin secretionIEAbiological_process
GO:0051001Negative regulation of nitric-oxide synthase activityIEAbiological_process
GO:0051966Regulation of synaptic transmission, glutamatergicIEAbiological_process
GO:0060135Maternal process involved in female pregnancyIEAbiological_process
GO:0060259Regulation of feeding behaviorIEAbiological_process
GO:0060405Regulation of penile erectionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83466318910.83082932260.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0510820983
GSE13712_SHEARDown-0.0021661785
GSE13712_STATICDown-0.0312848549
GSE19018Down-0.0100294045
GSE19899_A1Up0.0261666581
GSE19899_A2Up0.0352249353
PubMed_21979375_A1Up0.1192903397
PubMed_21979375_A2Down-0.0040192882
GSE35957Up0.0464085877
GSE36640Up0.1028192156
GSE54402Up0.0648433086
GSE9593Up0.0430437381
GSE43922Up0.0136292831
GSE24585Down-0.0711748026
GSE37065Down-0.0052298586
GSE28863_A1Down-0.0945989150
GSE28863_A2Down-0.0071492729
GSE28863_A3Up0.1779104771
GSE28863_A4Up0.0098256993
GSE48662Up0.0670527821

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NabiloneDB00486 APRD01127
SLV319DB05077 -
V24343DB05201 -
CP-945598DB05372 -
AVE-1625DB05750 -
RimonabantDB06155 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.