HCSGD entry for PLK5
1. General information
| Official gene symbol | PLK5 |
|---|---|
| Entrez ID | 126520 |
| Gene full name | polo-like kinase 5 |
| Other gene symbols | PLK-5 PLK5P SgK384ps |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002357 | Defense response to tumor cell | IDA | biological_process |
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006927 | Transformed cell apoptotic process | IMP | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0010976 | Positive regulation of neuron projection development | IDA | biological_process |
| GO:0031572 | G2 DNA damage checkpoint | IMP | biological_process |
| GO:0071363 | Cellular response to growth factor stimulus | IDA | biological_process |
| GO:2000045 | Regulation of G1/S transition of mitotic cell cycle | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8076765890 | 0.4496091562 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1085859139 |
| GSE13712_SHEAR | Down | -0.1479275621 |
| GSE13712_STATIC | Down | -0.2600404098 |
| GSE19018 | Up | 0.0374298396 |
| GSE19899_A1 | Down | -0.0162364011 |
| GSE19899_A2 | Up | 0.1240943258 |
| PubMed_21979375_A1 | Down | -0.2924364951 |
| PubMed_21979375_A2 | Down | -0.2497250085 |
| GSE35957 | Up | 0.0355726243 |
| GSE36640 | Down | -0.0146464063 |
| GSE54402 | Down | -0.0420183579 |
| GSE9593 | Down | -0.0420814295 |
| GSE43922 | Up | 0.0602780932 |
| GSE24585 | Up | 0.2147633780 |
| GSE37065 | Down | -0.0189896138 |
| GSE28863_A1 | Down | -0.1320347686 |
| GSE28863_A2 | Down | -0.2638667119 |
| GSE28863_A3 | Up | 0.3897569511 |
| GSE28863_A4 | Up | 0.1740747883 |
| GSE48662 | Down | -0.0172812140 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
