HCSGD entry for ACER1
1. General information
| Official gene symbol | ACER1 |
|---|---|
| Entrez ID | 125981 |
| Gene full name | alkaline ceramidase 1 |
| Other gene symbols | ALKCDase1 ASAH3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | ISS TAS | biological_process |
| GO:0008544 | Epidermis development | IEP | biological_process |
| GO:0010446 | Response to alkalinity | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0017040 | Ceramidase activity | IDA | molecular_function |
| GO:0019216 | Regulation of lipid metabolic process | IEA | biological_process |
| GO:0030148 | Sphingolipid biosynthetic process | IDA TAS | biological_process |
| GO:0030154 | Cell differentiation | IMP | biological_process |
| GO:0030216 | Keratinocyte differentiation | IEP | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046512 | Sphingosine biosynthetic process | IDA | biological_process |
| GO:0046514 | Ceramide catabolic process | ISS | biological_process |
| GO:0071277 | Cellular response to calcium ion | IDA | biological_process |
| GO:0071633 | Dihydroceramidase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4152379431 | 0.8905499487 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0035736876 |
| GSE13712_SHEAR | Down | -0.0215654694 |
| GSE13712_STATIC | Up | 0.2220742685 |
| GSE19018 | Up | 0.0157746504 |
| GSE19899_A1 | Up | 0.1224262704 |
| GSE19899_A2 | Up | 0.1442535664 |
| PubMed_21979375_A1 | Down | -0.2886160133 |
| PubMed_21979375_A2 | Down | -0.0243338680 |
| GSE35957 | Up | 0.0290044914 |
| GSE36640 | Up | 0.1298306262 |
| GSE54402 | Down | -0.0129880834 |
| GSE9593 | Up | 0.0341449411 |
| GSE43922 | Up | 0.0303212706 |
| GSE24585 | Down | -0.0472010034 |
| GSE37065 | Down | -0.1855521097 |
| GSE28863_A1 | Up | 0.1844702049 |
| GSE28863_A2 | Up | 0.0523140729 |
| GSE28863_A3 | Up | 0.3725197326 |
| GSE28863_A4 | Up | 0.0857181128 |
| GSE48662 | Up | 0.1140828641 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
