HCSGD entry for CCR3

1. General information

Official gene symbolCCR3
Entrez ID1232
Gene full namechemokine (C-C motif) receptor 3
Other gene symbolsCC-CKR-3 CD193 CKR3 CMKBR3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001938Positive regulation of endothelial cell proliferationIEAbiological_process
GO:0004950Chemokine receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006935ChemotaxisIEAbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0006968Cellular defense responseTASbiological_process
GO:0007155Cell adhesionTASbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0016493C-C chemokine receptor activityIEAmolecular_function
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0045766Positive regulation of angiogenesisIEA IMPbiological_process
GO:0070098Chemokine-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73176878540.82857225790.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0083803879
GSE13712_SHEARUp0.0183667619
GSE13712_STATICUp0.1354720865
GSE19018Up0.0222303955
GSE19899_A1Up0.1338688770
GSE19899_A2Up0.0690663652
PubMed_21979375_A1Down-0.0570756067
PubMed_21979375_A2Up0.0833763800
GSE35957Up0.1304516873
GSE36640Down-0.1559916662
GSE54402Down-0.0082706788
GSE9593Up0.0042001703
GSE43922Up0.0108036838
GSE24585Up0.0505506939
GSE37065Down-0.0496382862
GSE28863_A1Up0.0552067836
GSE28863_A2Down-0.0973530104
GSE28863_A3Up0.1892190343
GSE28863_A4Up0.0371877244
GSE48662Down-0.0622130876

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

22175510Injections of CCL11 inhibit neurogenesis in young mice, an effect likely mediated by CCR3 receptors on neural stem cells
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