HCSGD entry for ADSSL1

1. General information

Official gene symbolADSSL1
Entrez ID122622
Gene full nameadenylosuccinate synthase like 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0002376Immune system processNASbiological_process
GO:0003924GTPase activityIEAmolecular_function
GO:0004019Adenylosuccinate synthase activityIDA IEAmolecular_function
GO:0005525GTP bindingIEA NASmolecular_function
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006144Purine nucleobase metabolic processTASbiological_process
GO:0006164Purine nucleotide biosynthetic processIEAbiological_process
GO:0006167AMP biosynthetic processIDAbiological_process
GO:0006531Aspartate metabolic processIEAbiological_process
GO:0006541Glutamine metabolic processIEAbiological_process
GO:0009168Purine ribonucleoside monophosphate biosynthetic processIEA TASbiological_process
GO:0014850Response to muscle activityIEAbiological_process
GO:0035690Cellular response to drugIEAbiological_process
GO:0042301Phosphate ion bindingNASmolecular_function
GO:0042594Response to starvationIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0044208'de novo' AMP biosynthetic processIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046040IMP metabolic processIEAbiological_process
GO:0051015Actin filament bindingIEAmolecular_function
GO:0055086Nucleobase-containing small molecule metabolic processTASbiological_process
GO:0071257Cellular response to electrical stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15828776640.56453906390.78907051141.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2813567457
GSE13712_SHEARDown-0.2552353902
GSE13712_STATICDown-0.0894070629
GSE19018Up0.2464536663
GSE19899_A1Down-0.1706383535
GSE19899_A2Down-0.1298799055
PubMed_21979375_A1Up0.3210214452
PubMed_21979375_A2Down-0.2513093044
GSE35957Up0.0429445685
GSE36640Up0.0031004700
GSE54402Down-0.1629106756
GSE9593Down-0.1489428366
GSE43922Down-0.0018529005
GSE24585Up0.9535881599
GSE37065Up0.1629294340
GSE28863_A1Up0.1885238094
GSE28863_A2Up0.4573539677
GSE28863_A3Up0.2693466059
GSE28863_A4Down-0.0511496980
GSE48662Up0.0410548598

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Aspartic AcidDB00128 NUTR00016 | EXPT01823
HadacidinDB02109 EXPT01711
6-O-Phosphoryl Inosine MonophosphateDB03510 EXPT01873
Guanosine-5'-TriphosphateDB04137 EXPT01660
Guanosine-5'-DiphosphateDB04315 EXPT01573
Adenylosuccinic AcidDB04418 EXPT00146
Inosinic AcidDB04566 EXPT01874

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018589MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.