HCSGD entry for PLD4
1. General information
| Official gene symbol | PLD4 |
|---|---|
| Entrez ID | 122618 |
| Gene full name | phospholipase D family, member 4 |
| Other gene symbols | C14orf175 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004435 | Phosphatidylinositol phospholipase C activity | TAS | molecular_function |
| GO:0004630 | Phospholipase D activity | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006655 | Phosphatidylglycerol biosynthetic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
| GO:0070290 | NAPE-specific phospholipase D activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8025055051 | 0.4121237149 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0922863059 |
| GSE13712_SHEAR | Down | -0.0538724231 |
| GSE13712_STATIC | Up | 0.0949852495 |
| GSE19018 | Up | 0.0884133614 |
| GSE19899_A1 | Down | -0.0137555460 |
| GSE19899_A2 | Down | -0.1930587287 |
| PubMed_21979375_A1 | Up | 0.1406318935 |
| PubMed_21979375_A2 | Down | -0.1034733026 |
| GSE35957 | Up | 0.0815142893 |
| GSE36640 | Up | 0.0937965099 |
| GSE54402 | Up | 0.0692829180 |
| GSE9593 | Down | -0.0074660887 |
| GSE43922 | Up | 0.1879713982 |
| GSE24585 | Up | 0.0747894942 |
| GSE37065 | Down | -0.0387789052 |
| GSE28863_A1 | Down | -0.3556938177 |
| GSE28863_A2 | Down | -0.3528450884 |
| GSE28863_A3 | Down | -0.1122553180 |
| GSE28863_A4 | Up | 0.1290732402 |
| GSE48662 | Down | -0.1196365791 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016764 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
