HCSGD entry for ALKBH2

1. General information

Official gene symbolALKBH2
Entrez ID121642
Gene full namealkB, alkylation repair homolog 2 (E. coli)
Other gene symbolsABH2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005654NucleoplasmTAScellular_component
GO:0006281DNA repairTASbiological_process
GO:0006307DNA dealkylation involved in DNA repairIDA TASbiological_process
GO:0008198Ferrous iron bindingIDAmolecular_function
GO:0016706Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donorsIEAmolecular_function
GO:0035511Oxidative DNA demethylationIDAbiological_process
GO:0043734DNA-N1-methyladenine dioxygenase activityIDAmolecular_function
GO:0051747Cytosine C-5 DNA demethylase activityIDA TASmolecular_function
GO:0070989Oxidative demethylationTASbiological_process
GO:0080111DNA demethylationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98189562330.02292759010.99999024730.2913940608

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1514498849
GSE13712_SHEARDown-0.6263204208
GSE13712_STATICUp0.0180155973
GSE19018Down-0.4535670729
GSE19899_A1Down-0.0206639886
GSE19899_A2Down-0.3064136643
PubMed_21979375_A1Up0.0514559919
PubMed_21979375_A2Down-0.3369883853
GSE35957Down-0.8815457795
GSE36640Down-0.8933877258
GSE54402Down-0.0917103787
GSE9593Down-0.5353643546
GSE43922Up0.0327125914
GSE24585Down-0.3523887327
GSE37065Down-0.0851228219
GSE28863_A1Down-0.0531117033
GSE28863_A2Down-0.2040268390
GSE28863_A3Down-0.1721279093
GSE28863_A4Down-0.0429285627
GSE48662Down-0.2326559077

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Vitamin CDB00126 NUTR00001 | APRD00084 | EXPT00568 | DB09541

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.