HCSGD entry for CLPS


1. General information

Official gene symbolCLPS
Entrez ID1208
Gene full namecolipase, pancreatic
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processTASbiological_process
GO:0005576Extracellular regionTAScellular_component
GO:0006629Lipid metabolic processNASbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0008047Enzyme activator activityIEAmolecular_function
GO:0016042Lipid catabolic processIEAbiological_process
GO:0044241Lipid digestionTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49222950120.70867817330.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0891389923
GSE13712_SHEARUp0.1590289411
GSE13712_STATICUp0.0149253271
GSE19018Up0.1361881956
GSE19899_A1Up0.0475595662
GSE19899_A2Up0.1311666259
PubMed_21979375_A1Up0.2131888378
PubMed_21979375_A2Down-0.3608995324
GSE35957Up0.2713293492
GSE36640Up0.1131008361
GSE54402Up0.0107855715
GSE9593Up0.0203101381
GSE43922Up0.1176914801
GSE24585Up0.0150414282
GSE37065Down-0.0369305377
GSE28863_A1Up0.1019709033
GSE28863_A2Up0.0816780048
GSE28863_A3Down-0.0468831502
GSE28863_A4Up0.0151398386
GSE48662Down-0.3072385172

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

(Hydroxyethyloxy)Tri(Ethyloxy)OctaneDB04233 EXPT00817
METHOXYUNDECYLPHOSPHINIC ACIDDB08222 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

27368054Downstream of human HSCs, we observed decreasing levels of common lymphoid progenitors (CLPs), and increasing frequencies of megakaryocyte/erythrocyte progenitors (MEPs) with age, which could be linked to changes in lineage-affiliated gene expression patterns in aged human HSCs
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