HCSGD entry for ZFYVE27
1. General information
| Official gene symbol | ZFYVE27 |
|---|---|
| Entrez ID | 118813 |
| Gene full name | zinc finger, FYVE domain containing 27 |
| Other gene symbols | PROTRUDIN RP11-459F3.2 SPG33 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030424 | Axon | ISS | cellular_component |
| GO:0030425 | Dendrite | ISS | cellular_component |
| GO:0031175 | Neuron projection development | IDA | biological_process |
| GO:0032584 | Growth cone membrane | ISS | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | ISS | biological_process |
| GO:0055038 | Recycling endosome membrane | ISS | cellular_component |
| GO:0072659 | Protein localization to plasma membrane | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0124915429 | 0.9697141674 | 0.2791085739 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2836846542 |
| GSE13712_SHEAR | Down | -0.0459277449 |
| GSE13712_STATIC | Down | -0.1033748611 |
| GSE19018 | Up | 0.3619241892 |
| GSE19899_A1 | Up | 0.2083583049 |
| GSE19899_A2 | Up | 0.6509723901 |
| PubMed_21979375_A1 | Up | 0.9986111694 |
| PubMed_21979375_A2 | Up | 0.9497524088 |
| GSE35957 | Up | 0.1460057035 |
| GSE36640 | Up | 1.4618011874 |
| GSE54402 | Up | 0.2759466978 |
| GSE9593 | Up | 0.2786423479 |
| GSE43922 | Up | 0.4588440946 |
| GSE24585 | Down | -0.3131869067 |
| GSE37065 | Up | 0.1438485802 |
| GSE28863_A1 | Up | 0.1446666994 |
| GSE28863_A2 | Down | -0.0715064850 |
| GSE28863_A3 | Down | -0.1562923184 |
| GSE28863_A4 | Up | 0.0067315941 |
| GSE48662 | Up | 0.3869590719 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040082 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041333 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042621 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
