HCSGD entry for CLCN1

1. General information

Official gene symbolCLCN1
Entrez ID1180
Gene full namechloride channel, voltage-sensitive 1
Other gene symbolsCLC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005247Voltage-gated chloride channel activityIEAmolecular_function
GO:0005254Chloride channel activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0006936Muscle contractionTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0019227Neuronal action potential propagationIEAbiological_process
GO:0030554Adenyl nucleotide bindingIEAmolecular_function
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0042383SarcolemmaIEAcellular_component
GO:0044070Regulation of anion transportTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:1902476Chloride transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.39477267960.89649897420.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0226040115
GSE13712_SHEARDown-0.0262146238
GSE13712_STATICDown-0.1004847302
GSE19018Up0.1761791623
GSE19899_A1Down-0.0071734252
GSE19899_A2Up0.2543334323
PubMed_21979375_A1Up0.0264473337
PubMed_21979375_A2Down-0.0685121639
GSE35957Up0.1099321081
GSE36640Down-0.0107668582
GSE54402Up0.0156419719
GSE9593Up0.0614711173
GSE43922Up0.3675131605
GSE24585Up0.0294595426
GSE37065Down-0.0851090953
GSE28863_A1Down-0.0715886124
GSE28863_A2Down-0.0712778149
GSE28863_A3Up0.2628487648
GSE28863_A4Up0.1533971138
GSE48662Up0.1557663624

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.