HCSGD entry for AP1S1
1. General information
| Official gene symbol | AP1S1 |
|---|---|
| Entrez ID | 1174 |
| Gene full name | adaptor-related protein complex 1, sigma 1 subunit |
| Other gene symbols | AP19 CLAPS1 MEDNIK SIGMA1A WUGSC:H_DJ0747G18.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0005765 | Lysosomal membrane | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005905 | Coated pit | IEA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0006892 | Post-Golgi vesicle-mediated transport | TAS | biological_process |
| GO:0006898 | Receptor-mediated endocytosis | TAS | biological_process |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0009615 | Response to virus | IEP | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0030117 | Membrane coat | IEA | cellular_component |
| GO:0030121 | AP-1 adaptor complex | TAS | cellular_component |
| GO:0030659 | Cytoplasmic vesicle membrane | TAS | cellular_component |
| GO:0032588 | Trans-Golgi network membrane | TAS | cellular_component |
| GO:0050690 | Regulation of defense response to virus by virus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0110159530 | 0.4378817940 | 0.2650373857 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.9020652908 |
| GSE13712_SHEAR | Down | -0.3663470792 |
| GSE13712_STATIC | Up | 0.6048800387 |
| GSE19018 | Up | 0.5109347974 |
| GSE19899_A1 | Up | 0.1293110225 |
| GSE19899_A2 | Up | 1.1724939477 |
| PubMed_21979375_A1 | Down | -0.1643208190 |
| PubMed_21979375_A2 | Down | -0.1225671958 |
| GSE35957 | Up | 0.4643837101 |
| GSE36640 | Up | 0.7480470850 |
| GSE54402 | Up | 0.3989299606 |
| GSE9593 | Up | 1.1716432353 |
| GSE43922 | Up | 0.3785303241 |
| GSE24585 | Down | -0.2486919556 |
| GSE37065 | Down | -0.2226202700 |
| GSE28863_A1 | Down | -0.6904445088 |
| GSE28863_A2 | Down | -0.1165240720 |
| GSE28863_A3 | Down | -0.2526124075 |
| GSE28863_A4 | Up | 0.0223028025 |
| GSE48662 | Up | 0.3894630861 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | MIRT005815 | Microarray | Functional MTI (Weak) | 21282569 |
| hsa-miR-1 | MIMAT0000416 | MIRT023801 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
