HCSGD entry for SH2D1B
1. General information
| Official gene symbol | SH2D1B |
|---|---|
| Entrez ID | 117157 |
| Gene full name | SH2 domain containing 1B |
| Other gene symbols | EAT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002366 | Leukocyte activation involved in immune response | ISS | biological_process |
| GO:0002717 | Positive regulation of natural killer cell mediated immunity | ISS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0030674 | Protein binding, bridging | TAS | molecular_function |
| GO:0045089 | Positive regulation of innate immune response | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3488381027 | 0.9587886554 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0234771880 |
| GSE13712_SHEAR | Up | 0.1346820900 |
| GSE13712_STATIC | Up | 0.0572245121 |
| GSE19018 | Up | 0.2922199981 |
| GSE19899_A1 | Down | -0.0561157036 |
| GSE19899_A2 | Up | 0.1346990628 |
| PubMed_21979375_A1 | Up | 0.0935804272 |
| PubMed_21979375_A2 | Up | 0.1627832039 |
| GSE35957 | Up | 0.1759888671 |
| GSE36640 | Down | -0.0672261371 |
| GSE54402 | Up | 0.0825032483 |
| GSE9593 | Up | 0.0306052352 |
| GSE43922 | Up | 0.0693734897 |
| GSE24585 | Up | 0.2775836966 |
| GSE37065 | Down | -0.0211422594 |
| GSE28863_A1 | Up | 0.2726504414 |
| GSE28863_A2 | Up | 0.0759163695 |
| GSE28863_A3 | Down | -0.0973827792 |
| GSE28863_A4 | Down | -0.0036184714 |
| GSE48662 | Down | -0.0024018103 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022866 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
