HCSGD entry for AGAP3
1. General information
| Official gene symbol | AGAP3 |
|---|---|
| Entrez ID | 116988 |
| Gene full name | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 |
| Other gene symbols | AGAP-3 CENTG3 CRAG MRIP-1 cnt-g3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000060 | Protein import into nucleus, translocation | IEA | biological_process |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008060 | ARF GTPase activator activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0031593 | Polyubiquitin binding | IEA | molecular_function |
| GO:0032312 | Regulation of ARF GTPase activity | IEA | biological_process |
| GO:0034614 | Cellular response to reactive oxygen species | IEA | biological_process |
| GO:0043161 | Proteasome-mediated ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0071944 | Cell periphery | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3019436762 | 0.6790562099 | 0.9999004654 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0298348661 |
| GSE13712_SHEAR | Down | -0.4097456874 |
| GSE13712_STATIC | Down | -0.6951617856 |
| GSE19018 | Up | 0.0825150724 |
| GSE19899_A1 | Up | 0.0868973048 |
| GSE19899_A2 | Up | 0.4118427592 |
| PubMed_21979375_A1 | Up | 0.5898608198 |
| PubMed_21979375_A2 | Up | 0.2453252559 |
| GSE35957 | Down | -0.1062961344 |
| GSE36640 | Up | 0.1583554638 |
| GSE54402 | Up | 0.2026565797 |
| GSE9593 | Down | -0.1392157661 |
| GSE43922 | Up | 0.2105877962 |
| GSE24585 | Down | -0.3143374777 |
| GSE37065 | Down | -0.0657390585 |
| GSE28863_A1 | Down | -0.0157230243 |
| GSE28863_A2 | Up | 0.1374349091 |
| GSE28863_A3 | Up | 0.2397846412 |
| GSE28863_A4 | Down | -0.0655486611 |
| GSE48662 | Up | 0.2068377924 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-652-3p | MIMAT0003322 | MIRT039564 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045465 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
