HCSGD entry for AGAP1
1. General information
| Official gene symbol | AGAP1 |
|---|---|
| Entrez ID | 116987 |
| Gene full name | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
| Other gene symbols | AGAP-1 CENTG2 GGAP1 cnt-g2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005543 | Phospholipid binding | IDA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008060 | ARF GTPase activator activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0032312 | Regulation of ARF GTPase activity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1911485316 | 0.5358775350 | 0.8488646027 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3446300922 |
| GSE13712_SHEAR | Down | -0.5240701503 |
| GSE13712_STATIC | Down | -0.2300271554 |
| GSE19018 | Up | 0.2176439070 |
| GSE19899_A1 | Down | -0.0063594211 |
| GSE19899_A2 | Down | -0.0381365145 |
| PubMed_21979375_A1 | Down | -0.4915094600 |
| PubMed_21979375_A2 | Up | 0.6281713525 |
| GSE35957 | Down | -0.3293343628 |
| GSE36640 | Up | 0.3766606240 |
| GSE54402 | Up | 0.4431336211 |
| GSE9593 | Up | 0.1202261796 |
| GSE43922 | Up | 0.3701454397 |
| GSE24585 | Down | -0.0973033499 |
| GSE37065 | Down | -0.0576311129 |
| GSE28863_A1 | Up | 0.4051103316 |
| GSE28863_A2 | Up | 0.1725626356 |
| GSE28863_A3 | Up | 0.3429503129 |
| GSE28863_A4 | Down | -0.0246751169 |
| GSE48662 | Down | -0.0077576168 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT024193 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1225-3p | MIMAT0005573 | MIRT036541 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043133 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
