HCSGD entry for GRIN3A

1. General information

Official gene symbolGRIN3A
Entrez ID116443
Gene full nameglutamate receptor, ionotropic, N-methyl-D-aspartate 3A
Other gene symbolsGluN3A NMDAR-L NR3A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004972N-methyl-D-aspartate selective glutamate receptor activityIDA ISSmolecular_function
GO:0005234Extracellular-glutamate-gated ion channel activityIEAmolecular_function
GO:0005262Calcium channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0006816Calcium ion transportISSbiological_process
GO:0014069Postsynaptic densityIEAcellular_component
GO:0016020MembraneIDAcellular_component
GO:0016021Integral component of membraneNAScellular_component
GO:0016358Dendrite developmentIEAbiological_process
GO:0016594Glycine bindingIDAmolecular_function
GO:0017146N-methyl-D-aspartate selective glutamate receptor complexIDAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0042165Neurotransmitter bindingIEAmolecular_function
GO:0042802Identical protein bindingIPImolecular_function
GO:0043005Neuron projectionIDAcellular_component
GO:0043025Neuronal cell bodyIDAcellular_component
GO:0045202SynapseIDAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0045471Response to ethanolIDAbiological_process
GO:0048511Rhythmic processIEAbiological_process
GO:0051721Protein phosphatase 2A bindingISSmolecular_function
GO:0060134Prepulse inhibitionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27389217350.89054826560.97027131901.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0278425460
GSE13712_SHEARDown-0.0715978830
GSE13712_STATICDown-0.1156331782
GSE19018Up0.2184261040
GSE19899_A1Up0.1667365038
GSE19899_A2Down-0.0400837621
PubMed_21979375_A1Down-0.1488847911
PubMed_21979375_A2Up0.1247557234
GSE35957Up0.0592517430
GSE36640Up0.1880553555
GSE54402Down-0.0667024240
GSE9593Down-0.1831691510
GSE43922Up0.0069805863
GSE24585Up0.1337453779
GSE37065Down-0.0283906731
GSE28863_A1Down-0.0371164125
GSE28863_A2Down-0.0000424209
GSE28863_A3Up0.2566174405
GSE28863_A4Up0.0890981620
GSE48662Up1.6287695158

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027
TramadolDB00193 APRD00028
MethadoneDB00333 APRD00485
DextromethorphanDB00514 APRD00655
FelbamateDB00949 APRD00505
MemantineDB01043 APRD00221
ChloroprocaineDB01161 APRD00404
KetamineDB01221 APRD00493
TenocyclidineDB01520 -
RolicyclidineDB01549 -
PhencyclidineDB03575 EXPT03307
NeramexaneDB04926 -
AcamprosateDB00659 APRD00661
GavestinelDB06741 -
AtomoxetineDB00289 APRD00614
PentobarbitalDB00312 APRD01174
GabapentinDB00996 APRD00015
DehydroepiandrosteroneDB01708 EXPT00519 | DB06593
MilnacipranDB04896 -
KetobemidoneDB06738 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.