HCSGD entry for KLHDC3
1. General information
| Official gene symbol | KLHDC3 |
|---|---|
| Entrez ID | 116138 |
| Gene full name | kelch domain containing 3 |
| Other gene symbols | PEAS RP1-20C7.3 dJ20C7.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000790 | Nuclear chromatin | IDA | cellular_component |
| GO:0003682 | Chromatin binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006987 | Activation of signaling protein activity involved in unfolded protein response | TAS | biological_process |
| GO:0007131 | Reciprocal meiotic recombination | NAS | biological_process |
| GO:0030968 | Endoplasmic reticulum unfolded protein response | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8329755632 | 0.0395564454 | 0.9999902473 | 0.3749071994 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4639175141 |
| GSE13712_SHEAR | Down | -0.4810055082 |
| GSE13712_STATIC | Down | -0.3072085378 |
| GSE19018 | Up | 0.1628438279 |
| GSE19899_A1 | Down | -0.2174861785 |
| GSE19899_A2 | Up | 0.3658208011 |
| PubMed_21979375_A1 | Up | 0.6438683675 |
| PubMed_21979375_A2 | Down | -0.1441725859 |
| GSE35957 | Up | 0.5288698387 |
| GSE36640 | Down | -0.1903894305 |
| GSE54402 | Up | 0.0699292416 |
| GSE9593 | Down | -0.4905586352 |
| GSE43922 | Down | -0.0437492204 |
| GSE24585 | Down | -0.3142547196 |
| GSE37065 | Down | -0.4816248379 |
| GSE28863_A1 | Up | 0.1565113418 |
| GSE28863_A2 | Up | 0.2148242148 |
| GSE28863_A3 | Down | -0.5084693062 |
| GSE28863_A4 | Down | -0.3843701357 |
| GSE48662 | Up | 0.1774227105 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030532 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036861 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038784 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-3p | MIMAT0004493 | MIRT038971 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043209 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045462 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
