HCSGD entry for DIS3L
1. General information
| Official gene symbol | DIS3L |
|---|---|
| Entrez ID | 115752 |
| Gene full name | DIS3 mitotic control homolog (S. cerevisiae)-like |
| Other gene symbols | DIS3L1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000175 | 3'-5'-exoribonuclease activity | IDA IMP | molecular_function |
| GO:0000177 | Cytoplasmic exosome (RNase complex) | IDA | cellular_component |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0016075 | RRNA catabolic process | IDA IMP | biological_process |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | IDA IMP | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | IDA IMP | biological_process |
| GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic | IDA IMP | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9810397781 | 0.0067021504 | 0.9999902473 | 0.1643525140 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3271017335 |
| GSE13712_SHEAR | Down | -0.2310740872 |
| GSE13712_STATIC | Down | -0.1801487892 |
| GSE19018 | Down | -0.6919261411 |
| GSE19899_A1 | Down | -0.9710598913 |
| GSE19899_A2 | Down | -1.6741260095 |
| PubMed_21979375_A1 | Down | -0.6700193796 |
| PubMed_21979375_A2 | Down | -0.0941014642 |
| GSE35957 | Down | -0.4270224702 |
| GSE36640 | Down | -1.4951671488 |
| GSE54402 | Down | -0.5037534929 |
| GSE9593 | Up | 0.1065705407 |
| GSE43922 | Down | -0.7154088030 |
| GSE24585 | Down | -0.2059174945 |
| GSE37065 | Up | 0.0246843825 |
| GSE28863_A1 | Down | -0.0166195725 |
| GSE28863_A2 | Up | 0.2223777640 |
| GSE28863_A3 | Down | -0.1768142746 |
| GSE28863_A4 | Down | -0.0170913819 |
| GSE48662 | Up | 0.0160261489 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024295 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026419 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-671-3p | MIMAT0004819 | MIRT037770 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040874 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
