HCSGD entry for ARHGEF25


1. General information

Official gene symbolARHGEF25
Entrez ID115557
Gene full nameRho guanine nucleotide exchange factor (GEF) 25
Other gene symbolsGEFT p63RhoGEF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneISScellular_component
GO:0030016MyofibrilISScellular_component
GO:0030017SarcomereIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72677344330.07120079780.99999024730.5037839247

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3300274329
GSE13712_SHEARDown-0.0026768405
GSE13712_STATICDown-0.0537689099
GSE19018Up0.0326884598
GSE19899_A1Down-0.1534894011
GSE19899_A2Down-0.3843600356
PubMed_21979375_A1Down-0.6402624536
PubMed_21979375_A2Down-0.6259533633
GSE35957Down-0.1846571131
GSE36640Down-0.0262764708
GSE54402Down-0.3715800346
GSE9593Up0.3427741664
GSE43922Down-1.0412295957
GSE24585Up0.1854552951
GSE37065Down-0.3137886825
GSE28863_A1Up0.0109654122
GSE28863_A2Up0.2796788362
GSE28863_A3Up0.3325131569
GSE28863_A4Up0.0257642131
GSE48662Up0.5430570291

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-328-3pMIMAT0000752MIRT043803CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049431CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.