HCSGD entry for FCHO2
1. General information
| Official gene symbol | FCHO2 |
|---|---|
| Entrez ID | 115548 |
| Gene full name | FCH domain only 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001786 | Phosphatidylserine binding | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005546 | Phosphatidylinositol-4,5-bisphosphate binding | ISS | molecular_function |
| GO:0005886 | Plasma membrane | ISS | cellular_component |
| GO:0005905 | Coated pit | IDA | cellular_component |
| GO:0010324 | Membrane invagination | ISS | biological_process |
| GO:0030136 | Clathrin-coated vesicle | IDA | cellular_component |
| GO:0035091 | Phosphatidylinositol binding | ISS | molecular_function |
| GO:0048268 | Clathrin coat assembly | IMP | biological_process |
| GO:0072583 | Clathrin-mediated endocytosis | IMP | biological_process |
| GO:0072659 | Protein localization to plasma membrane | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2133359903 | 0.4101818434 | 0.8900327469 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1917378921 |
| GSE13712_SHEAR | Up | 0.0793805049 |
| GSE13712_STATIC | Down | -0.1973175526 |
| GSE19018 | Up | 0.5597612410 |
| GSE19899_A1 | Up | 0.0445878884 |
| GSE19899_A2 | Down | -0.0769720211 |
| PubMed_21979375_A1 | Up | 0.1871124332 |
| PubMed_21979375_A2 | Down | -0.0133792994 |
| GSE35957 | Up | 0.3360197263 |
| GSE36640 | Up | 0.3956746846 |
| GSE54402 | Down | -0.1084558607 |
| GSE9593 | Up | 0.2392651678 |
| GSE43922 | Down | -0.0202046679 |
| GSE24585 | Up | 0.3406495032 |
| GSE37065 | Up | 0.3810654775 |
| GSE28863_A1 | Down | -0.3333602630 |
| GSE28863_A2 | Down | -0.0526533174 |
| GSE28863_A3 | Down | -0.5967008723 |
| GSE28863_A4 | Down | -0.4087656834 |
| GSE48662 | Up | 0.1691098987 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002703 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002703 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028083 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-181d-5p | MIMAT0002821 | MIRT041166 | CLASH | Functional MTI (Weak) | 23622248 |
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