HCSGD entry for OMA1
1. General information
| Official gene symbol | OMA1 |
|---|---|
| Entrez ID | 115209 |
| Gene full name | OMA1 zinc metallopeptidase |
| Other gene symbols | 2010001O09Rik DAB1 MPRP-1 YKR087C ZMPOMA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002024 | Diet induced thermogenesis | IMP | biological_process |
| GO:0004222 | Metalloendopeptidase activity | IEA IMP | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0006006 | Glucose metabolic process | IMP | biological_process |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006515 | Misfolded or incompletely synthesized protein catabolic process | IMP | biological_process |
| GO:0006629 | Lipid metabolic process | IMP | biological_process |
| GO:0006950 | Response to stress | IDA | biological_process |
| GO:0010637 | Negative regulation of mitochondrial fusion | IMP | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031966 | Mitochondrial membrane | IDA | cellular_component |
| GO:0034982 | Mitochondrial protein processing | IEA | biological_process |
| GO:0042407 | Cristae formation | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0097009 | Energy homeostasis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7380887124 | 0.0964813343 | 0.9999902473 | 0.5919711189 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3158335057 |
| GSE13712_SHEAR | Up | 0.1739166975 |
| GSE13712_STATIC | Up | 0.3931132154 |
| GSE19018 | Down | -0.2350887468 |
| GSE19899_A1 | Up | 0.0489276200 |
| GSE19899_A2 | Up | 0.0734905987 |
| PubMed_21979375_A1 | Down | -0.9460172023 |
| PubMed_21979375_A2 | Down | -0.1144761284 |
| GSE35957 | Down | -0.0402692135 |
| GSE36640 | Up | 0.4462284711 |
| GSE54402 | Down | -0.8611478102 |
| GSE9593 | Down | -0.1902945424 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.0302845978 |
| GSE28863_A2 | Down | -0.1407033486 |
| GSE28863_A3 | Down | -0.0442790090 |
| GSE28863_A4 | Down | -0.0533422359 |
| GSE48662 | Up | 0.0566490925 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000883 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000884 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT021287 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT025592 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
