HCSGD entry for OSBPL1A
1. General information
| Official gene symbol | OSBPL1A |
|---|---|
| Entrez ID | 114876 |
| Gene full name | oxysterol binding protein-like 1A |
| Other gene symbols | ORP-1 ORP1 OSBPL1B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005543 | Phospholipid binding | NAS | molecular_function |
| GO:0005622 | Intracellular | IC | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005765 | Lysosomal membrane | TAS | cellular_component |
| GO:0005770 | Late endosome | IDA | cellular_component |
| GO:0006869 | Lipid transport | IEA | biological_process |
| GO:0008203 | Cholesterol metabolic process | NAS | biological_process |
| GO:0015485 | Cholesterol binding | IDA | molecular_function |
| GO:0016192 | Vesicle-mediated transport | NAS | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3543476920 | 0.0255815395 | 0.9999902473 | 0.3071768704 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2543338447 |
| GSE13712_SHEAR | Up | 0.4283980760 |
| GSE13712_STATIC | Up | 0.4740395479 |
| GSE19018 | Up | 0.7329989262 |
| GSE19899_A1 | Down | -1.4994689736 |
| GSE19899_A2 | Down | -0.4544225681 |
| PubMed_21979375_A1 | Down | -1.0035926835 |
| PubMed_21979375_A2 | Down | -0.7733469525 |
| GSE35957 | Up | 0.7293955812 |
| GSE36640 | Down | -0.0665686827 |
| GSE54402 | Down | -1.0383999792 |
| GSE9593 | Up | 0.6044746644 |
| GSE43922 | Down | -0.8362411401 |
| GSE24585 | Up | 0.0016128235 |
| GSE37065 | Down | -0.0657402414 |
| GSE28863_A1 | Down | -0.1252080696 |
| GSE28863_A2 | Up | 0.2460927129 |
| GSE28863_A3 | Down | -0.5564718938 |
| GSE28863_A4 | Up | 0.0898151081 |
| GSE48662 | Up | 0.0935893924 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019536 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-146a-5p | MIMAT0000449 | MIRT021270 | Microarray | Functional MTI (Weak) | 18057241 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030733 | Microarray | Functional MTI (Weak) | 18591254 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
