HCSGD entry for ESCO1
1. General information
| Official gene symbol | ESCO1 |
|---|---|
| Entrez ID | 114799 |
| Gene full name | establishment of sister chromatid cohesion N-acetyltransferase 1 |
| Other gene symbols | A930014I12Rik CTF ECO1 EFO1 ESO1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000785 | Chromatin | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006275 | Regulation of DNA replication | IMP | biological_process |
| GO:0007062 | Sister chromatid cohesion | IEA | biological_process |
| GO:0016746 | Transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0034421 | Post-translational protein acetylation | IMP | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2837932867 | 0.6933255044 | 0.9828583026 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1866015255 |
| GSE13712_SHEAR | Up | 0.2904900198 |
| GSE13712_STATIC | Up | 0.0018654036 |
| GSE19018 | Up | 0.2169169229 |
| GSE19899_A1 | Up | 0.2046650085 |
| GSE19899_A2 | Down | -0.0221157373 |
| PubMed_21979375_A1 | Up | 0.2727034044 |
| PubMed_21979375_A2 | Up | 0.3472427922 |
| GSE35957 | Down | -0.0635580374 |
| GSE36640 | Down | -0.2562158555 |
| GSE54402 | Up | 0.0441470456 |
| GSE9593 | Down | -0.0321836761 |
| GSE43922 | Up | 0.0686257973 |
| GSE24585 | Down | -0.1722840214 |
| GSE37065 | Up | 0.0940111792 |
| GSE28863_A1 | Up | 0.2609214244 |
| GSE28863_A2 | Up | 0.1527523261 |
| GSE28863_A3 | Down | -0.5449040907 |
| GSE28863_A4 | Up | 0.0864667141 |
| GSE48662 | Down | -0.4256066522 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26029164 | Furthermore, we investigated the correlated expression patterns of Cdc14B, ESCO1, KPNA5, MAP3K3, and CSIG during cell cycle and senescence progression, which imply the important pathways CSIG regulating cell cycle and senescence |
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