HCSGD entry for PGLYRP3

1. General information

Official gene symbolPGLYRP3
Entrez ID114771
Gene full namepeptidoglycan recognition protein 3
Other gene symbolsPGRP-Ialpha PGRPIA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002221Pattern recognition receptor signaling pathwayIDAbiological_process
GO:0005576Extracellular regionIEAcellular_component
GO:0005622IntracellularNAScellular_component
GO:0007165Signal transductionIDAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008745N-acetylmuramoyl-L-alanine amidase activityIEAmolecular_function
GO:0009253Peptidoglycan catabolic processIEAbiological_process
GO:0016019Peptidoglycan receptor activityIDAmolecular_function
GO:0016020MembraneNAScellular_component
GO:0016045Detection of bacteriumIDAbiological_process
GO:0032689Negative regulation of interferon-gamma productionIEAbiological_process
GO:0032827Negative regulation of natural killer cell differentiation involved in immune responseIEAbiological_process
GO:0042834Peptidoglycan bindingIDAmolecular_function
GO:0044117Growth of symbiont in hostIEAbiological_process
GO:0045087Innate immune responseNASbiological_process
GO:0050830Defense response to Gram-positive bacteriumIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71631488170.48483795830.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0795711862
GSE13712_SHEARDown-0.0012079958
GSE13712_STATICDown-0.0163215622
GSE19018Down-0.0395847069
GSE19899_A1Up0.0032669012
GSE19899_A2Down-0.2291288639
PubMed_21979375_A1Down-0.3179875970
PubMed_21979375_A2Up0.2466031625
GSE35957Up0.3203704057
GSE36640Down-0.0264690636
GSE54402Up0.1472930433
GSE9593Down-0.0283973916
GSE43922Down-0.0448195530
GSE24585Up0.0208889157
GSE37065Down-0.0660615436
GSE28863_A1Down-0.0395362415
GSE28863_A2Up0.1453841827
GSE28863_A3Up0.0996300508
GSE28863_A4Down-0.0533713057
GSE48662Down-0.0604318764

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINEDB04736 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.