HCSGD entry for CYP2U1
1. General information
| Official gene symbol | CYP2U1 |
|---|---|
| Entrez ID | 113612 |
| Gene full name | cytochrome P450, family 2, subfamily U, polypeptide 1 |
| Other gene symbols | P450TEC SPG49 SPG56 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016712 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | IEA | molecular_function |
| GO:0019369 | Arachidonic acid metabolic process | TAS | biological_process |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0070330 | Aromatase activity | IEA | molecular_function |
| GO:0097267 | Omega-hydroxylase P450 pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2971225219 | 0.0089478135 | 0.9965377548 | 0.1873630867 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3353172634 |
| GSE13712_SHEAR | Down | -0.7136722134 |
| GSE13712_STATIC | Down | -0.4214950471 |
| GSE19018 | Up | 0.2257879038 |
| GSE19899_A1 | Down | -0.4780869558 |
| GSE19899_A2 | Down | -1.2667380525 |
| PubMed_21979375_A1 | Down | -2.6517114094 |
| PubMed_21979375_A2 | Down | -1.3680222517 |
| GSE35957 | Up | 0.7595524853 |
| GSE36640 | Up | 1.1452396345 |
| GSE54402 | Down | -1.5041626477 |
| GSE9593 | Up | 0.5692292748 |
| GSE43922 | Down | -1.5547740471 |
| GSE24585 | Up | 0.4207513098 |
| GSE37065 | Down | -0.0593427121 |
| GSE28863_A1 | Up | 0.1324917570 |
| GSE28863_A2 | Up | 0.4621940833 |
| GSE28863_A3 | Up | 0.1481875653 |
| GSE28863_A4 | Down | -0.1661361938 |
| GSE48662 | Up | 0.3930895410 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019811 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020782 | Reporter assay;Other | Functional MTI | 20584899 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022645 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031184 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
