HCSGD entry for EXOSC8
1. General information
| Official gene symbol | EXOSC8 |
|---|---|
| Entrez ID | 11340 |
| Gene full name | exosome component 8 |
| Other gene symbols | CIP3 EAP2 OIP2 RP11-421P11.3 RRP43 Rrp43p bA421P11.3 p9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000178 | Exosome (RNase complex) | IDA | cellular_component |
| GO:0000288 | Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | TAS | biological_process |
| GO:0004532 | Exoribonuclease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006364 | RRNA processing | IEA | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0017091 | AU-rich element binding | IDA | molecular_function |
| GO:0043928 | Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9925056875 | 0.0008934539 | 0.9999902473 | 0.0566338902 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4187305808 |
| GSE13712_SHEAR | Up | 0.0513977646 |
| GSE13712_STATIC | Down | -0.1583404329 |
| GSE19018 | Down | -0.5247864704 |
| GSE19899_A1 | Down | -1.2723417983 |
| GSE19899_A2 | Down | -1.6983543889 |
| PubMed_21979375_A1 | Down | -1.2497482156 |
| PubMed_21979375_A2 | Down | -2.5570037256 |
| GSE35957 | Down | -1.0905955224 |
| GSE36640 | Down | -1.6685534028 |
| GSE54402 | Down | -0.3135742200 |
| GSE9593 | Down | -0.5755487100 |
| GSE43922 | Down | -0.9847761640 |
| GSE24585 | Down | -0.0817525093 |
| GSE37065 | Down | -0.2472249125 |
| GSE28863_A1 | Down | -0.0730662648 |
| GSE28863_A2 | Up | 0.0688222193 |
| GSE28863_A3 | Down | -0.2655695048 |
| GSE28863_A4 | Up | 0.2677308316 |
| GSE48662 | Down | -0.4742096267 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030408 | Microarray | Functional MTI (Weak) | 19748357 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
