HCSGD entry for U2AF2
1. General information
| Official gene symbol | U2AF2 |
|---|---|
| Entrez ID | 11338 |
| Gene full name | U2 small nuclear RNA auxiliary factor 2 |
| Other gene symbols | U2AF65 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000398 | MRNA splicing, via spliceosome | IC TAS | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | IDA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006397 | MRNA processing | IEA TAS | biological_process |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
| GO:0048025 | Negative regulation of mRNA splicing, via spliceosome | IDA | biological_process |
| GO:0070742 | C2H2 zinc finger domain binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6869069222 | 0.3871909426 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0341712006 |
| GSE13712_SHEAR | Up | 0.1044332874 |
| GSE13712_STATIC | Down | -0.0882417278 |
| GSE19018 | Down | -0.1905127057 |
| GSE19899_A1 | Down | -0.0026913716 |
| GSE19899_A2 | Up | 0.2710190286 |
| PubMed_21979375_A1 | Up | 0.4559531165 |
| PubMed_21979375_A2 | Down | -0.0764775316 |
| GSE35957 | Down | -0.2066659354 |
| GSE36640 | Down | -0.3015434580 |
| GSE54402 | Up | 0.2991878294 |
| GSE9593 | Down | -0.1581185282 |
| GSE43922 | Up | 0.1115275021 |
| GSE24585 | Down | -0.4198942944 |
| GSE37065 | Down | -0.2272050708 |
| GSE28863_A1 | Up | 0.0576721479 |
| GSE28863_A2 | Down | -0.3084667506 |
| GSE28863_A3 | Up | 0.0206767389 |
| GSE28863_A4 | Up | 0.2067108341 |
| GSE48662 | Up | 0.2221114025 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-455-3p | MIMAT0004784 | MIRT037893 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-671-5p | MIMAT0003880 | MIRT039299 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-542-5p | MIMAT0003340 | MIRT039351 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040214 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040739 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042954 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-210-3p | MIMAT0000267 | MIRT047003 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048235 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049199 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
