HCSGD entry for STK38
1. General information
| Official gene symbol | STK38 |
|---|---|
| Entrez ID | 11329 |
| Gene full name | serine/threonine kinase 38 |
| Other gene symbols | NDR NDR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IDA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006464 | Cellular protein modification process | IDA | biological_process |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0031435 | Mitogen-activated protein kinase kinase kinase binding | IPI | molecular_function |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043407 | Negative regulation of MAP kinase activity | IDA | biological_process |
| GO:0070688 | MLL5-L complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6872978382 | 0.3007786102 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2531317798 |
| GSE13712_SHEAR | Up | 0.1242964738 |
| GSE13712_STATIC | Up | 0.0584367898 |
| GSE19018 | Up | 0.0253925490 |
| GSE19899_A1 | Up | 0.0527442445 |
| GSE19899_A2 | Down | -0.1376728847 |
| PubMed_21979375_A1 | Down | -0.2538701308 |
| PubMed_21979375_A2 | Down | -0.3335932930 |
| GSE35957 | Up | 0.1489378200 |
| GSE36640 | Up | 0.3220843313 |
| GSE54402 | Down | -0.0286605086 |
| GSE9593 | Up | 0.1997770745 |
| GSE43922 | Down | -0.0051647761 |
| GSE24585 | Up | 0.1521621801 |
| GSE37065 | Down | -0.0932468790 |
| GSE28863_A1 | Up | 0.1187015531 |
| GSE28863_A2 | Up | 0.2184584906 |
| GSE28863_A3 | Down | -0.5617492718 |
| GSE28863_A4 | Down | -0.4290228237 |
| GSE48662 | Up | 0.3682881705 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023042 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027196 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031271 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031919 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-454-3p | MIMAT0003885 | MIRT039243 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052031 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
