HCSGD entry for MGAT4A
1. General information
| Official gene symbol | MGAT4A |
|---|---|
| Entrez ID | 11320 |
| Gene full name | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| Other gene symbols | GNT-IV GNT-IVA GnT-4a |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006491 | N-glycan processing | TAS | biological_process |
| GO:0008454 | Alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5632598571 | 0.9083211162 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0451431821 |
| GSE13712_SHEAR | Down | -0.1384174934 |
| GSE13712_STATIC | Up | 0.0277649568 |
| GSE19018 | Up | 0.1424137650 |
| GSE19899_A1 | Down | -0.0285155248 |
| GSE19899_A2 | Up | 0.1731430015 |
| PubMed_21979375_A1 | Up | 0.0777891755 |
| PubMed_21979375_A2 | Up | 0.0275184010 |
| GSE35957 | Up | 0.0739097962 |
| GSE36640 | Up | 0.2742899103 |
| GSE54402 | Up | 0.0714457524 |
| GSE9593 | Down | -0.0664044189 |
| GSE43922 | Up | 0.2029408542 |
| GSE24585 | Down | -0.1941678772 |
| GSE37065 | Up | 0.0429645599 |
| GSE28863_A1 | Down | -0.0244434469 |
| GSE28863_A2 | Up | 0.0728632791 |
| GSE28863_A3 | Up | 0.0772962252 |
| GSE28863_A4 | Up | 0.0021547828 |
| GSE48662 | Up | 0.0169598634 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016995 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030689 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031454 | Sequencing | Functional MTI (Weak) | 20371350 |
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