HCSGD entry for CDCA5
1. General information
| Official gene symbol | CDCA5 |
|---|---|
| Entrez ID | 113130 |
| Gene full name | cell division cycle associated 5 |
| Other gene symbols | SORORIN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000082 | G1/S transition of mitotic cell cycle | IDA | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000775 | Chromosome, centromeric region | TAS | cellular_component |
| GO:0000790 | Nuclear chromatin | ISS | cellular_component |
| GO:0003682 | Chromatin binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA ISS | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005694 | Chromosome | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006302 | Double-strand break repair | IMP | biological_process |
| GO:0007064 | Mitotic sister chromatid cohesion | IMP | biological_process |
| GO:0007067 | Mitosis | IDA | biological_process |
| GO:0007076 | Mitotic chromosome condensation | IMP | biological_process |
| GO:0007080 | Mitotic metaphase plate congression | IMP | biological_process |
| GO:0008278 | Cohesin complex | IDA | cellular_component |
| GO:0051329 | Mitotic interphase | ISS | biological_process |
| GO:0071922 | Regulation of cohesin localization to chromatin | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9693532541 | 0.0000540823 | 0.9999902473 | 0.0119621849 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3587045819 |
| GSE13712_SHEAR | Down | -0.5790964392 |
| GSE13712_STATIC | Down | -0.4208574338 |
| GSE19018 | Down | -0.1297021264 |
| GSE19899_A1 | Down | -1.2854986123 |
| GSE19899_A2 | Down | -4.0521387477 |
| PubMed_21979375_A1 | Down | -3.0989354170 |
| PubMed_21979375_A2 | Down | -4.1495337270 |
| GSE35957 | Down | -3.0464460025 |
| GSE36640 | Down | -4.2054724775 |
| GSE54402 | Down | -0.8134395813 |
| GSE9593 | Down | -1.3791772515 |
| GSE43922 | Down | -0.8066802137 |
| GSE24585 | Down | -0.0748263497 |
| GSE37065 | Down | -0.2362315222 |
| GSE28863_A1 | Down | -0.1181620667 |
| GSE28863_A2 | Up | 0.7504584067 |
| GSE28863_A3 | Up | 0.0953282713 |
| GSE28863_A4 | Up | 0.2866357725 |
| GSE48662 | Down | -1.9188382185 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016488 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-18b-5p | MIMAT0001412 | MIRT042416 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050732 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | NA | hsa-miR-331-3p | 19996289 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
