HCSGD entry for SCN11A
1. General information
| Official gene symbol | SCN11A |
|---|---|
| Entrez ID | 11280 |
| Gene full name | sodium channel, voltage-gated, type XI, alpha subunit |
| Other gene symbols | NAV1.9 NaN SCN12A SNS-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001518 | Voltage-gated sodium channel complex | IEA | cellular_component |
| GO:0005248 | Voltage-gated sodium channel activity | IEA | molecular_function |
| GO:0006814 | Sodium ion transport | TAS | biological_process |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | TAS | biological_process |
| GO:0042493 | Response to drug | TAS | biological_process |
| GO:0044299 | C-fiber | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5272586376 | 0.9358792751 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0232461865 |
| GSE13712_SHEAR | Up | 0.1281566736 |
| GSE13712_STATIC | Down | -0.1211533573 |
| GSE19018 | Down | -0.1375207227 |
| GSE19899_A1 | Up | 0.0794255894 |
| GSE19899_A2 | Down | -0.0192090653 |
| PubMed_21979375_A1 | Up | 0.1026510950 |
| PubMed_21979375_A2 | Up | 0.2381473637 |
| GSE35957 | Down | -0.0407376178 |
| GSE36640 | Up | 0.0290084368 |
| GSE54402 | Up | 0.0009238858 |
| GSE9593 | Up | 0.1021222225 |
| GSE43922 | Up | 0.0188993242 |
| GSE24585 | Up | 0.3221452144 |
| GSE37065 | Up | 0.0708014374 |
| GSE28863_A1 | Down | -0.0048852274 |
| GSE28863_A2 | Up | 0.1525913091 |
| GSE28863_A3 | Up | 0.1173313726 |
| GSE28863_A4 | Up | 0.0926167739 |
| GSE48662 | Up | 0.0172554571 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Zonisamide | DB00909 | APRD00004 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047837 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048261 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
